{"id":868,"date":"2018-02-24T12:35:36","date_gmt":"2018-02-24T16:35:36","guid":{"rendered":"http:\/\/www.inolivent.recherche.usherbrooke.ca\/?page_id=868"},"modified":"2024-04-10T15:09:07","modified_gmt":"2024-04-10T19:09:07","slug":"inolivent-from-2001-to-2016","status":"publish","type":"page","link":"https:\/\/www.inolivent.ca\/","title":{"rendered":"Research group Inolivent \/ Groupe de recherche Inolivent"},"content":{"rendered":"

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Recherche sur la ventilation liquide<\/h1>\n

De nombreuses donn\u00e9es bibliographiques sugg\u00e8rent un changement radical de l’assistance respiratoire en rempla\u00e7ant le m\u00e9lange gazeux traditionnel par un liquide respiratoire comme le perfluorocarbone liquide (PFOB) qui peut dissoudre une grande quantit\u00e9 d’oxyg\u00e8ne et de dioxyde de carbone tout en \u00e9tant biochimiquement stable et bio-inerte.<\/p>\n

Cependant, seul un ventilateur liquidien peut garantir la ventilation des poumons avec un liquide respiratoire en toute s\u00e9curit\u00e9. Depuis 2001, le groupe de recherche Inolivent a d\u00e9velopp\u00e9 de nombreux prototypes de ventilateurs liquidiens pour mener des recherches exp\u00e9rimentales. Nos prototypes ont d\u00e9montr\u00e9 leur efficacit\u00e9 lors d’exp\u00e9riences sur des mammif\u00e8res de 460 g \u00e0 79,5 kg.<\/p>\n

La ventilation liquide totale permet une transition remarquablement stable vers la vie extra-ut\u00e9rine dans un mod\u00e8le d’agneau extr\u00eamement pr\u00e9matur\u00e9. Le perfectionnement de notre ventilateur liquidien Inolivent-9 et de ses algorithmes de commande cible les d\u00e9fis sp\u00e9cifiques de la n\u00e9onatalit\u00e9 en soins intensifs.<\/p>\n

Research in Liquid ventilation<\/h1>\n

Large literature data suggest a radical change in ventilator support by replacing the traditional gas mixture with a breathable liquid.\u00a0 Since the 70s, perfluorocarbon liquids have been identified as the best candidates to be used in liquid ventilation due to their high oxygen and carbon dioxide solubility. In addition, they are biochemically stable and bio-inert molecules, available as medical grade products. However, only a liquid ventilator can ensure a safe and efficient liquid ventilation.<\/p>\n

Since 2001, we have developed many prototypes of liquid ventilator used to conduct research in liquid ventilation\u00a0 with different animal models. Our prototypes have demonstrated their efficiency during animal experiments from 460 g to 79.5 Kg.<\/p>\n

Total liquid ventilation allows for remarkably stable transition to extrauterine life in an extremely preterm lamb model.\u00a0The further development of our Inolivent-9 liquid ventilator and its control algorithms targets the specific challenges of neonatal intensive care.<\/p>\n","protected":false},"excerpt":{"rendered":"

Recherche sur la ventilation liquide De nombreuses donn\u00e9es bibliographiques sugg\u00e8rent un changement radical de l’assistance respiratoire en rempla\u00e7ant le m\u00e9lange gazeux traditionnel par un liquide respiratoire comme le perfluorocarbone liquide (PFOB) qui peut dissoudre une grande quantit\u00e9 d’oxyg\u00e8ne et de dioxyde de carbone tout en \u00e9tant biochimiquement stable et bio-inerte. Cependant, seul un ventilateur liquidien […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-868","page","type-page","status-publish","hentry"],"aioseo_notices":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P3zpRR-e0","_links":{"self":[{"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=\/wp\/v2\/pages\/868","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=868"}],"version-history":[{"count":160,"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=\/wp\/v2\/pages\/868\/revisions"}],"predecessor-version":[{"id":1266,"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=\/wp\/v2\/pages\/868\/revisions\/1266"}],"wp:attachment":[{"href":"https:\/\/www.inolivent.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=868"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}